Description

This Chicken Alfredo Casserole is a creamy, cheesy baked pasta dish that combines tender chicken, al dente penne, and rich Alfredo sauce, topped with melted mozzarella and Parmesan cheese. Perfect for a comforting family meal, it’s easy to prepare and full of flavorful ingredients.

Ingredients

Units Scale

For the Pasta and Chicken:

16 ounce box penne pasta
2 Tablespoons olive oil
3 cups cubed chicken breasts
salt and pepper, to taste

For the Alfredo Sauce:

2 (15 ounce) jars Alfredo sauce
8 ounce block cream cheese, softened
1 cup whole milk
3 cloves garlic, minced
1 teaspoon Italian seasoning
1/2 teaspoon salt
1/4 teaspoon black pepper

For the Topping and Garnish:

2 cups shredded mozzarella cheese (divided)
1 cup grated Parmesan cheese (divided)
chopped fresh parsley or dried parsley, for garnish (optional)

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Instructions

Preheat oven and prepare baking dish: Preheat your oven to 350°F. Spray a 9×13-inch baking dish with nonstick cooking spray and set aside.
Cook pasta: Cook the penne pasta according to package directions until al dente. Drain well and set aside.
Cook chicken: Heat olive oil in a medium skillet over medium heat. Add the cubed chicken, season with salt and pepper, and cook until golden brown and fully cooked, about 7-10 minutes. Remove from heat and set aside.
Make the sauce: In a large mixing bowl, combine Alfredo sauce, softened cream cheese, whole milk, minced garlic, Italian seasoning, salt, and black pepper. Mix well until smooth and creamy.
Combine pasta and chicken with sauce: Add the cooked pasta and chicken to the bowl with sauce, stirring until evenly coated. Mix in 1 cup shredded mozzarella and ½ cup grated Parmesan cheese.
Assemble casserole: Pour the mixture into the prepared baking dish. Sprinkle the remaining mozzarella and Parmesan cheese evenly over the top. Cover with foil.
Bake: Bake uncovered for 25 minutes. Then remove foil and bake for an additional 10 minutes, or until the cheese is melted and bubbly.
Garnish and serve: Garnish with chopped parsley if desired. Serve hot and enjoy this creamy, cheesy chicken Alfredo casserole.

Notes

You can replace the chicken with cooked shrimp or turkey for variation.
If you prefer a thinner sauce, add a splash more milk or Alfredo sauce before mixing with pasta.
For extra flavor, sprinkle red pepper flakes over the top before baking.
Leftovers can be stored in an airtight container for up to 3 days and reheated in the microwave.

Nutrition

Serving Size: 1 slice (about 1/8 of the casserole)
Calories: 520 kcal
Sugar: 8 g
Sodium: 820 mg
Fat: 26 g
Saturated Fat: 13 g
Unsaturated Fat: 11 g
Trans Fat: 0 g
Carbohydrates: 55 g
Fiber: 3 g
Protein: 32 g
Cholesterol: 125 mg