Beef Taco Casserole with Biscuit Base Recipe

If you’re anything like me and love a comforting meal that’s easy to throw together yet tastes like a fiesta in every bite, then you’re going to adore this Beef Taco Casserole with Biscuit Base Recipe. It’s one of those dishes that feels like a big warm hug after a long day, combining familiar taco flavors with a chewy, buttery biscuit bottom. Trust me, once you try this casserole, you’ll find yourself making it again and again!

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Why You’ll Love This Recipe

  • Effortless Comfort Food: Combines hearty beef, melty cheese, and a soft biscuit base for an all-in-one meal you’ll crave.
  • Simple Ingredients: No fancy or hard-to-find items—just pantry staples and a few fresh veggies.
  • Great for Families: My family goes crazy for this casserole, and it’s perfect for weeknight dinners or casual gatherings.
  • Customizable: Easy to tweak with your favorite toppings or spice level. I’ll share some variations below!

Ingredients You’ll Need

This Beef Taco Casserole with Biscuit Base Recipe strikes a nice balance between bold taco flavors and creamy, cheesy layers. Each ingredient plays its part to build those layers of flavor and texture that make this dish extra special. Here’s what you’ll want to have on hand—plus some tips to help you pick the best!

Flat lay of fresh lean ground beef in a small mound, one whole red bell pepper, one whole yellow onion, a small white bowl of finely diced green chiles, a small white bowl of mild salsa, a small white bowl with pale yellow biscuit mix powder, a small white bowl of water, a small white bowl of sour cream, a small white bowl of creamy mayonnaise, a small white bowl of golden shredded cheddar cheese fiesta blend, and a small white bowl of light brown taco seasoning powder, arranged in perfect symmetry on a clean white marble surface, soft natural light, photo taken with an iPhone, professional food photography style, fresh ingredients, white ceramic bowls, no bottles, no duplicates, no utensils, no packaging --ar 2:3 --v 7 --p m7354615311229779997 - Beef Taco Casserole with Biscuit Base, taco casserole recipes, easy beef casserole, comfort food casserole, cheesy taco bake
  • Lean Ground Beef: I prefer lean ground beef for less grease, but you can choose 80/20 for a juicier result.
  • Red Bell Pepper: Adds a sweet crunch and vibrant color—plus it pairs beautifully with the savory beef.
  • Yellow Onion: A must for that classic sautéed base flavor in Mexican-inspired dishes.
  • Taco Seasoning Mix: You can use a store-bought packet or make your own blend to control the salt and spice.
  • Biscuit Mix: Like Bisquick, this is your shortcut to a flaky and tender biscuit base without all the fuss of scratch dough.
  • Water: Easily hydrates the biscuit mix to create your biscuit dough quickly.
  • Cooking Spray: To grease the casserole dish—helps the biscuit base release easily and prevents sticking.
  • Sour Cream: Gives richness and a subtle tang that balances the savory layers.
  • Mayonnaise: Adds creamy moisture without overpowering—plus it keeps the texture smooth.
  • Diced Green Chiles: Brings a nice mild heat and little pops of flavor throughout the cream layer.
  • Cheddar Cheese, Fiesta Blend: A mix of cheeses adds melty, gooey goodness; I love the fiesta blend for extra flavor.
  • Garlic Powder: Boosts the savory notes and works well with all the other spices.
  • Salsa (Mild): I like mild salsa here so everyone can enjoy it, but feel free to bump up the heat if you prefer!
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Note: You’ll find the complete list of ingredients, along with their exact measurements, in the printable recipe card at the bottom of this post.

Variations

I love how flexible this Beef Taco Casserole with Biscuit Base Recipe is! Over the years, I’ve tweaked it based on whatever I have in my fridge or the preferences of guests—and it always turns out delicious. Feel free to make it your own!

  • Spicy Version: Add a diced jalapeño with the vegetables or swap mild salsa for a spicy chipotle salsa—my husband swears by this version.
  • Makes it Vegetarian: Use a plant-based ground “beef” or swap with black beans and corn for a hearty meatless casserole.
  • Cheese Swap: Try pepper jack or a Mexican blend cheese for a different cheesy vibe.
  • Extra Veggies: Toss in corn kernels, chopped zucchini, or even diced tomatoes to boost nutrition and color.

How to Make Beef Taco Casserole with Biscuit Base Recipe

Step 1: Preheat and Brown Your Beef

Start by setting your oven to 350℉ so it’s ready for baking later. Next, heat a large skillet over medium-high heat and add the ground beef. Break it up with your spoon and cook until it’s no longer pink. This usually takes about 5-7 minutes. One trick I’ve learned is to avoid crowding the pan so the beef browns nicely instead of steaming. Once browned, drain the excess fat to keep the casserole from getting greasy.

Step 2: Whip Up the Biscuit Dough and Parbake

While the beef cooks, mix the biscuit mix and water in a medium bowl. I like using my hands here to make sure everything comes together evenly; it gives you the best texture. Spray your 9×13-inch casserole dish with cooking spray, then press the dough out evenly all the way to the edges. Pop it into the oven for just 5-8 minutes until the dough sets and gets a light golden color. Don’t overbake at this stage—the biscuit will finish cooking once you add the rest of the layers.

Step 3: Sauté Veggies and Season Your Beef

After you remove the biscuit base from the oven, add your chopped onion and red bell pepper directly to the skillet with the cooked beef. Stir and cook for about 4 minutes until veggies soften. Then sprinkle in the taco seasoning and mix well to coat everything in those bold flavors. Remove the skillet from heat when combined—this mixture forms the hearty layer just above your biscuit base.

Step 4: Layer the Casserole

Spread the beef and veggie mixture evenly over the biscuit base in the casserole dish. Now, in another bowl, combine sour cream, mayonnaise, the drained diced green chiles, ¾ cup shredded cheese, and garlic powder until smooth. This creamy layer adds richness and some gentle heat from the chiles—spread it carefully over the beef so you preserve those layers.

Step 5: Add Salsa and Finish with Cheese

Drop small spoonfuls of salsa evenly over the sour cream mixture—you don’t need to spread it, as those touches of salsa will burst with flavor while baking. Finally, sprinkle the remaining ¾ cup of shredded cheese over the top to create that beautiful golden crust.

Step 6: Bake Until Hot and Bubbly

Return the casserole to the oven, uncovered, for about 30 minutes. You’ll want to see the cheese melty and bubbling and make sure everything is heated through. I love peeking in occasionally—the aroma alone will make your kitchen smell irresistible!

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Pro Tips for Making Beef Taco Casserole with Biscuit Base Recipe

  • Don’t Skip Draining the Beef: Removing excess grease keeps your casserole from being soggy and lets other flavors shine.
  • Parbake the Biscuit Base: This ensures the biscuit cooks through without getting mushy under the toppings.
  • Layer Carefully: Spreading the creamy mixture gently avoids mixing layers and keeps each bite distinct and tasty.
  • Use Fresh Veggies: Fresh onion and red bell pepper add sweetness and crunch that canned veggies can’t beat.

How to Serve Beef Taco Casserole with Biscuit Base Recipe

A thick square piece of lasagna with four visible layers sits on a dark plate against a black background. The bottom layer is creamy with melted cheese, followed by a layer of browned ground meat mixed with cheese. Above it is another creamy melted cheese layer mixed with meat, topped by a thick layer of melted yellow and white cheese that stretches in strings above the lasagna. Small green herb pieces are sprinkled on top, and some melted cheese drips down the sides, creating a rich and gooey appearance. photo taken with an iphone --ar 2:3 --v 7 - Beef Taco Casserole with Biscuit Base, taco casserole recipes, easy beef casserole, comfort food casserole, cheesy taco bake

Garnishes

I always top my slices with a sprinkle of fresh cilantro and a dollop of sour cream or guacamole for some bright, cool contrast. Sometimes a few sliced green onions or a squeeze of fresh lime juice really brings it all together. I find these simple garnishes make this cozy casserole feel extra special on the plate.

Side Dishes

To keep the meal balanced, I usually serve this casserole with a crisp green salad dressed lightly or some Mexican-style rice and beans. Corn on the cob or a side of roasted veggies also pairs nicely, especially if you want to add more veggies to the plate without fuss.

Creative Ways to Present

For gatherings, I like to bake this casserole in individual ramekins or muffin tins—it’s fun to serve and perfect for portion control. You can also spoon portions into small tortilla bowls for a playful taco twist that guests adore. Try layering avocado slices or topping with pickled jalapeños for a colorful, eye-catching presentation.

Make Ahead and Storage

Storing Leftovers

Leftovers reheat beautifully and actually taste better the next day once the flavors meld. I store the casserole tightly covered with foil or plastic wrap in the fridge for up to 3 days. Just be sure to keep it chilled until reheating to maintain the texture of the biscuit base.

Freezing

I’ve frozen this casserole after baking—wrapped tightly in foil and placed in an airtight container. When thawed overnight in the fridge, it reheats well in the oven. Freezing does soften the biscuit base a bit, so if you plan to freeze, consider parbaking the base just slightly less before layering.

Reheating

Reheat leftover beef taco casserole in a 350℉ oven for 15-20 minutes until warmed through and bubbly. I avoid microwaving because it can make the biscuit base soggy. If you’re short on time, cover with foil during reheating to keep moisture in, then uncover at the end to crisp the cheese topping.

FAQs

  1. Can I use homemade biscuit dough instead of biscuit mix?

    Absolutely! Homemade biscuit dough works wonderfully and adds a more buttery, flaky texture to the base. Just be sure to parbake it slightly before adding layers to ensure it finishes cooking properly.

  2. Is there a way to make this recipe healthier?

    Yes—use ground turkey or lean ground beef to reduce fat, swap mayonnaise for Greek yogurt for added protein, and load up on extra veggies like corn, zucchini, or black beans to boost nutrition.

  3. Can I make this dairy-free?

    To make this casserole dairy-free, use dairy-free cheese alternatives and substitute sour cream and mayonnaise with plant-based versions. Double-check your biscuit mix to ensure it doesn’t include dairy or opt for a homemade dairy-free biscuit dough.

  4. How spicy is this casserole?

    This recipe is mild by default thanks to the mild salsa and green chiles, making it family-friendly. You can easily add heat with jalapeños, spicy salsa, or extra taco seasoning if you want more kick.

Final Thoughts

I absolutely love how this Beef Taco Casserole with Biscuit Base Recipe turns out every single time—it’s hearty, cheesy, and bursting with familiar, satisfying flavors. When I first tried making it, I was skeptical a biscuit base would work, but it adds such a fun twist and it’s always a hit with my family. If you want an easy, crowd-pleasing meal that feels like a celebration of taco night but with less mess, I wholeheartedly recommend giving this recipe a go. You’ll be amazed at how simple comfort food can taste so spectacular!

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Beef Taco Casserole with Biscuit Base Recipe

Beef Taco Casserole with Biscuit Base Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 4.7 from 70 reviews
  • Author: Emily
  • Prep Time: 15 minutes
  • Cook Time: 40 minutes
  • Total Time: 55 minutes
  • Yield: 8 servings 1x
  • Category: Casserole
  • Method: Baking
  • Cuisine: American, Southwestern

Description

Cattle Drive Casserole is a hearty, layered dish featuring seasoned ground beef, vegetables, and a creamy cheesy topping atop a golden biscuit crust. Perfect for family dinners, this casserole combines Southwest flavors with a comforting, baked biscuit base for a satisfying meal.


Ingredients

Scale

Meat and Vegetables

  • 1.5 pounds Lean Ground Beef
  • 1 Red Bell Pepper, seeded, chopped
  • 1 Yellow Onion, chopped
  • 1 ounce Taco Seasoning Mix

Biscuit Layer

  • 2 ½ cups Biscuit Mix (like Bisquick)
  • 1 cup Water
  • Cooking Spray (like Pam)

Sour Cream Mixture

  • ½ cup Sour Cream
  • ½ cup Mayonnaise
  • 4 ounces Diced Green Chiles, drained
  • 1 ½ cups Cheddar Cheese, Fiesta Blend, shredded, divided
  • 1 teaspoon Garlic Powder

Topping

  • ½ cup Salsa, mild


Instructions

  1. Preheat the Oven: Set your oven to 350°F (175°C) to ensure it’s hot and ready for baking the biscuit layer and later the entire casserole.
  2. Cook the Ground Beef: Heat a large skillet over medium-high heat. Add the ground beef, breaking it apart with a spoon or spatula. Stir occasionally and cook until no pink remains. Drain excess fat from the pan. While this cooks, begin preparing the biscuit dough.
  3. Prepare the Biscuit Dough: In a medium mixing bowl, combine the biscuit mix and water. Stir well or use your hands to blend until a consistent dough forms. Spray a 9 x 13-inch casserole dish with cooking spray, press the dough evenly into the dish, spreading it out to cover the bottom and edges. Bake this biscuit base in the preheated oven for 5 to 8 minutes until set and lightly golden. Remove and keep oven temperature steady.
  4. Cook the Vegetables: Add the chopped onions and red bell pepper to the skillet with the cooked ground beef. Sauté together for about 4 minutes until vegetables soften. Stir in the taco seasoning thoroughly then remove from heat.
  5. Assemble the Layers: Evenly spread the cooked ground beef and vegetable mixture over the baked biscuit crust in the casserole dish.
  6. Prepare the Sour Cream Layer: In a separate medium bowl, mix sour cream, mayonnaise, drained diced green chiles, ¾ cup of shredded cheddar cheese, and garlic powder until smooth and well combined. Gently spread this creamy mixture over the ground beef layer in the casserole dish.
  7. Add Salsa and Cheese: Drop spoonfuls of mild salsa sporadically over the sour cream layer without spreading it. Then sprinkle the remaining ¾ cup of shredded cheddar cheese evenly over the top.
  8. Bake: Return the casserole, uncovered, to the oven. Bake for 30 minutes or until the casserole is hot, bubbly, and cheese is melted and lightly browned.

Notes

  • Use lean ground beef to reduce excess fat and grease in the casserole.
  • For spicier flavor, choose a hotter salsa or add jalapeño chiles instead of mild salsa.
  • Leftover casserole can be refrigerated for up to 3 days and reheated in the oven or microwave.
  • Biscuit mix can be substituted with homemade biscuit dough if desired.
  • Ensure the biscuit layer is baked before adding toppings to prevent sogginess.

Nutrition

  • Serving Size: 1 slice (approx. 1/8 of casserole)
  • Calories: 400 kcal
  • Sugar: 3 g
  • Sodium: 700 mg
  • Fat: 25 g
  • Saturated Fat: 10 g
  • Unsaturated Fat: 12 g
  • Trans Fat: 0 g
  • Carbohydrates: 25 g
  • Fiber: 2 g
  • Protein: 25 g
  • Cholesterol: 75 mg

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